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9.10.0 INTERFERON TREATMENT OF HCV WITH CIRRHOSIS

In patients with hepatitis C who have cirrhosis, the rate of sustained response following interferon therapy is only half that of patients without cirrhosis. Although it has been suggested that a higher dose regime in patients with cirrhosis may improve response, this remains largely untested. The results of a recent Australian study where cirrhotic patients were given an intense interferon program of 4.5 MIU daily for 24 weeks suggests that future studies in cirrhosis should be carried out exploring higher doses and longer durations of therapy. - “Interferon Treatment of HCV with Cirrhosis,” Journal of Viral Hepatitis 1997 ;4:85-88



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