The effects of methadone can alleviate possible painful symptoms of hepatitis
C. Although this may be helpful, it can camouflage early signs of liver
damage (if it develops). Flu-like hepatitis C symptoms may give the
impression that you are on prescription pills. If this causes problems at
the clinic where you receive your methadone, it may be useful to remind
them of the complicating effect of hepatitis C symptoms.
If you experience flu-like symptoms of hepatitis C, these symptoms should not
be misinterpreted as withdrawal symptoms from opiates.
People should be careful with methadone dosages and aware of their real tolerance for drugs. This is especially important if liver damage is severe. - Hepatitis C Council of NSW