At one time, Interferon alone was considered standard therapy. It is now used alone only when the patient has some condition, such as a heart problem, that doesn’t allow the use of ribavirin.
Nautilus Biotech is developing a set of improved IFN-alpha molecules with a
longer half-life, without using pegylation technology. Patents have been
applied for, and funding seems to be in place www.nautilusbiotech.com).