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1.1.5a SEXUAL TRANSMISSION

The risk of sexual transmission of hepatitis C virus has not been thoroughly investigated but appears to be minimal. Some studies have shown no risk of passing hepatitis C on to a sexual partner, others have shown only a very low risk. The United States Centers for Disease Control and Prevention (CDC), as well as the British Columbia Centre for Disease Control do not recommend a change in sexual practices for those engaged in a long-term relationship with one sexual partner. However, people with acute illness and multiple sexual partners may be at greater risk and should use condoms to reduce the risk of acquiring or transmitting hepatitis C as well as other sexually transmitted infections. The risk is increased if the HCV positive partner is immunocompromised because the virus titer in the blood may be increased under those circumstances. Sex during the menstrual period should be avoided, due to the blood contact at that time. There is also some speculation about the possibility of transmission piggybacked on the genital herpes virus through genital lesions.

The reason that many studies say “multiple sexual partners” when referring to the risk of sexual transmission of HCV is that people who have multiple sexual partners have a greater risk of contracting other sexually transmitted diseases which can cause open sores and lesions. And with those open sores and lesions you are at greater risk for blood contact. Also, it is thought that the hepatitis C virus tends to “piggyback” on the herpes virus, and if you have herpes you are at much greater risk of contracting or transmitting the virus.

According to a report in the Archives of Internal Medicine, sexual transmission of HCV occurs at a rate of about 1% per year in at-risk partners, and shows that periodic serum immune globulin prophylaxis for sexual partners is protective.

Transmission of the virus “...occurred only in partners of HCV-infected patients with active liver disease,” the researchers report. They add an “intriguing” finding that patients who became infected during the study were older and had longer relationships with their partners compared with those who did not become infected. - Arch Intern Med 1997;157:1537-1544

A report from Health Canada, “Hepatitis C Prevention and Control: A Public Health Consensus,” June 1999, p.6, recommends that:

  • People with multiple partners should practice safer sex.

  • Longstanding sexual partners do not need to change sexual practices if one of them is found to be infected with hepatitis C

A recent study in The Lancet, 356:9223:42-43 (June 2000) detected the hepatitis C virus in the semen of infected men. The doctors concluded that “the presence of HCV-RNA in semen is a strong argument in favour of HCV sexual transmission from men to women.” However, HCV viral loads detected in semen were low, which suggests that the risk of HCV sexual transmission is probably also low.



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